Light diffraction study of single skeletal muscle fibres

Polymorphism of myofibrillar proteins of rabbit skeletal-muscle fibres. An electrophoretic study of single fibres.

Rabbit predominantly fast-twitch-fibre and predominantly slow-twitch-fibre skeletal muscles of the hind limbs, the psoas, the diaphragm and the masseter muscles were fibre-typed by one-dimensional polyacrylamide-gel electrophoresis of the myofibrillar proteins of chemically skinned single fibres. Investigation of the distribution of fast-twitch-fibre and slow-twitch-fibre isoforms of myosin lig...

Light Diffraction by Single Striated Muscle Fibers

LIGHT DIFFRACTION BY SINGLE STRIATED MUSCLE FIBERSf

Muscle fibres: applications for the study of the metabolic consequences of enzyme deficiencies in skeletal muscle.

Mitochondrial function in saponin-permeabilized muscle fibres can be studied by high-resolution respirometry, laser-excited fluorescence spectroscopy and fluorescence microscopy. We applied these techniques to study metabolic effects of changes in the pattern of mitochondrial enzymes in skeletal muscle of patients with chronic progressive external ophthalmoplegia or Kearns-Sayre syndrome harbou...

Coupling light into optical fibres near the diffraction limit

The burgeoning field of astrophotonics explores the interface between astronomy and photonics. Important applications include photonic OH suppression at near-infrared wavelengths, and integrated photonic spectroscopy. These new photonic mechanisms are not well matched to conventional multi-mode fibre bundles, and are best fed with single or few-mode fibres. We envisage the largest gains in astr...